Pediatric Autoimmune Neuropsychiatric Disorders (PANDAS) may present with
one or more of the following symptoms in conjunction with their OCD ( Obsessive compulsive behavior) and/or tics:
1. ADHD symptoms (hyperactivity, inattention, fidgety)
2. Separation anxiety (child is “clingy” and has difficulty separating from his/her caregivers; for example, the child may not want to be in a different room in the house from his/her parents)
3. Mood changes (irritability, sadness, emotional lability)
4. Sleep disturbance
5. Night- time bed wetting and/or day- time urinary frequency
6. Fine/gross motor changes (e.g. changes in handwriting)
7. Joint pains
There is an association with a strep infection or a positive throat culture for strep.
Usually it is age 3 years to puberty in onset of symptoms
and the symptoms can get worse and better, worse and better over time.
There is also an association of PANDAS with Lyme disease as well.
PANDAS, the diagnosis is based on the diagnostic criteria of
OCD and or a tic disorder
Pediatric onset of symptoms
episodic course of symptom severity
Association with a group A beta hemolytic streptococcal infection