About four months ago a 12 year old girl who had crohn’s and was in remission came to see me because she had a relapse of her crohn’s after two years in remission. She presented with severe abdominal pain ( like 10/10 in severity). Her evaluation in the possible causes of her relapse yielded a positive Lyme titer- showing exposure. She was treated with Doxycycline and now a few months later dad reports that her abdominal pain is minimal.
Take home lesson- One of the triggers of what we call Crohn’s disease, can be lyme and its coinfections which include bartonella, mycoplasma, ehrlichia, anaplasma, and rocky mountain spotted fever. In a person with a predisposition to autoimmune disease and a family history of autoimmune disease, these infections could trigger the autoimmune process.