MTHFR gene and its associated conditions

I am a physician in central NJ knowledgeable in MtHFR and treating patients with Crohn’s, autism, epilepsy, attention defecit, depression,  Heart attacks, stroke, blood clots, hardening of the arteries, schizophrenia, alzheimer’s, bipolar, parkinson’s, insomnia, irritability, forgetfulness, and restless leg syndrome, and autoimmune diseases  such as multiple sclerosis, ulcerative colitis, pernicious anemia, celiac, rheumatoid arthritis, chronic fatigue, lupus, fibromyalgia have in common?  Any of these conditions may be associated with a methylene tetrahydrolfolate reductase (MTHFR) deficiency. Miscarriages, neural tube defects and birth defects, anxiety, panic, generalized muscle pain and tenderness or even chronic headaches, or tremors, numbing and tingling in an area of the body may be related to the folic acid cycle and enzymes working at less than their optimal activity. Giving supplemental folate or folic acid may not be the answer if the body is unable to convert the folic acid due to an enzyme problem. The reduced enzyme activity of one or more of over 30 enzymes (MTHFR C677T. MTHFR A1298C, MTHFR P39P, SHMT C1420T, CBS C699T, CBS A360A, CBS N212N, AHCY 01, AHCY 02, AHCY 19, VDR Bsm, VDR Taq, VDR Fok, MAO A R297R, COMT V158M, COMT H62H, COMT -61 P199P, ACAT 1-02, MTRR S257T, MTRR A66G, NOS 3 D298E, MTRR H595Y, MTRR K350A, MTRR R415T, MTRR A664A, MTR A2756G, SUOX S370S, BHMT 01, BHMT 02, BHMT 04, BHMT 08) may account for any or a combination of the above symptoms – See more at: